Drug utilization study of diuretics in children with hydrocephalus

Indrawijaya, Yen Yen Ari, Sumarno, Sumarno, Suryaningtyas, Wihasto and Husna, Nuril Auliya (2021) Drug utilization study of diuretics in children with hydrocephalus. Presented at 1st International Pharmacy Ulul Albab Conference and Seminar 2021 (PLANAR), 31 Jul 2021, Malang.

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Abstract

Hydrocephalus is a condition characterized by a dynamic imbalance between formation and absorption of cerebrospinal fluid that increases the size of intracranial space of the brain and, in some situations, an extension of the outer space of the brain with or without increased ventricular size.This study aimed to examine the use of diuretics and identify drug therapy problems in hospitalized children with hydrocephalus through the medical record.The study design is observational retrospective with time-limited sampling based on data in medical records at 2010-2013 periods, found 17 of 70 patients using diuretics therapy.There are three categories of diuretic which are used were mannitol (70.6%), acetazolamide (23.5%), and a combination of mannitol and acetazolamide (5.9%).Diuretics can be used for pre-op, post-op, and pre & post-op on all types of hydrocephalus. Still, the specific use of diuretics may be caused by variations in comorbid diagnoses, clinical data, and laboratory data for each patient.Adverse drug reactions are potentially dominant in DTP analysis, and these are 7 of 17 patients.Monitoring of serum electrolytes such as sodium and potassium is needed because it decreases are potential adverse drug reactions of diuretics.

Item Type:	Conference (Paper)
Keywords:	diuretics; hydrocephalus; child; drug utilization study (DUS)
Subjects:	11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111502 Clinical Pharmacology and Therapeutics
Divisions:	Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User:	Yen Yen Indrawijaya
Date Deposited:	13 Jun 2022 13:04

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