Decreased cTnT levels heart failure patients with routinely taking standard therapy

Indrawijaya, Yen Yen Ari, Suharjono, Suharjono, Retnowati, Endang and Rahman, Gilang Mauladi (2023) Decreased cTnT levels heart failure patients with routinely taking standard therapy. Presented at The 3rd Annual Symposium on Hajj and Umrah Medicine (ANSHAR) 2022, 22-23 Oct 2022, Malang, Indonesia.

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Abstract

Extreme physical stressors like thirst increase the risk of non-communicable diseases, especially heart failure (HF). Cardiac patients should ensure adequate supplies of and adherence to medications. They must avoid crowds, perform certain rituals, and report to the nearest health center if symptoms indicate cardiac decompensation. However, in acute or chronic HF with reduced or preserved ejection fraction (EF), elevated cardiac troponin (cTn) levels carry prognostic value for adverse outcomes. A prospective observational study aimed to evaluate levels of cTnT before and after administration of standard therapy and treatment history in hospitalized HF patients. The samples were collected by consecutive sampling and obtained from 30 patients from May-July 2017. The results showed that the number of patients whose cTnT levels decreased by ten patients (30.68 vs. 12.96 pg/ml; p=0.005) increased by 12 patients (31.00 vs. 76.75 pg/ml; p=0.002) and persistent by eight patients (40.70 vs. 42.41 pg/ml; p=0.779). Changes in serum cTnT levels and the clinical condition of the patient, possible to consider the factors of the patient's clinical condition that affect cTnT levels. There was a decrease in levels of cTnT in patients who regularly took medication (10 patients, 29.74 vs. 17.97 pg/ml; p=0.037), while in patients who did not take medication regularly, there was an increase in levels of cTnT (20 patients, 35.35 vs. 60.51 pg/ml; p=0.025). Evaluation of patients' adherence to heart failure therapy has ruled out major risk factors, such as patients with uncontrolled heart disease, to reduce casualties during Hajj.

Item Type:	Conference (Paper)
Keywords:	cTnT; adherence; heart failure; standard therapy
Subjects:	11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111502 Clinical Pharmacology and Therapeutics
Divisions:	Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User:	Yen Yen Indrawijaya
Date Deposited:	11 Apr 2023 09:30

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