Pengaruh pemberian timbal (Pb) dosis kronis secara oral terhadap peningkatan penanda kerusakan organ pada mencit

Setiawan, Abdul Malik (2012) Pengaruh pemberian timbal (Pb) dosis kronis secara oral terhadap peningkatan penanda kerusakan organ pada mencit. el-Hayah, 3 (1). pp. 24-28. ISSN 2086-0064

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Abstract

Several kind of heavy metals that present in the environment are considered as toxic substance to human and animal. Lead (Pb) is one of heavy metals that increase in use for the last decade. Lead toxicity to human had wide influence in medical aspect, from nerve problem, bone metabolics disturbance until liver and renal failure. This experiment tried to found out the effect of cronic oral lead consupmtion to lead plasma rate in mice. Design of this experiment is true research experiment to test wheater there is an effect of oral lead consumption to acumulation of lead in blood plasma of mice. The dose devided to two kinds, medium dose (50 ppm) and high dose (100 ppm). The results show increase of lead accumulation in blood plasma of the mice compared to control group.

Item Type: Journal Article
Subjects: 11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111506 Toxicology (incl. Clinical Toxicology)
Divisions: Faculty of Medical and Health Sciences > Department of Medical Education
Depositing User: Abdul Malik Setiawan
Date Deposited: 09 Feb 2017 09:04

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