Dosage and administration length of (L) urban decrease the level of SOD and MDA and improve brain histological condition of rats

Muchtaromah, Bayyinatul and Ahmad, Mujahidin and Suyono, Suyono and Romaidi, Romaidi and Bahri, Samsul and Kumalasari, Hasnia Prinha (2016) Dosage and administration length of (L) urban decrease the level of SOD and MDA and improve brain histological condition of rats. Jurnal Teknologi, 5 (78). pp. 57-61. ISSN 2180–3722

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Abstract

Medicinal plants have been used for treating many kinds of illness due to their safety, cheap and easy to be accessed by all level of society. This study was aimed to determine the effect of the dosage forms (fresh, boiled and ethanol extracted) and the duration (24 and 42 days) of medicinal plant Centella asiatica to the levels of superoxide dismutase (SOD), malondialdehyde (MDA) and the histopathology of diabetic rat brain. The results showed that administration of various dosage forms of C. asiatica were able to increase the number of pyramid cells and neuroglia in the cerebrum significantly (P <0.01) but had no significant effect (P>0.01) at the administration length and the interaction between both treatments. This finding resulted in the new traditional herbal medicine that can be used for treating degenerative disorders on nervous system.

Item Type: Journal Article
Keywords: Daylight factor %DF; window to wall ratio (WWR); window to floor ratio (WFR)
Subjects: 06 BIOLOGICAL SCIENCES > 0604 Genetics > 060499 Genetics not elsewhere classified
Divisions: Faculty of Mathematics and Sciences > Department of Biology
Depositing User: Bayyinatul Muchtaromah
Date Deposited: 18 Apr 2017 02:14

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