Penyakit malaria dan mekanisme kerja obat-obat antimalaria

Mutiah, Roihatul (2012) Penyakit malaria dan mekanisme kerja obat-obat antimalaria. Alchemy, 2 (1). pp. 80-91. ISSN 2460-6871

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Abstract

Malaria is one of theinfectious diseaseis stillaproblem ofthe world withhigh mortality. Therapeutic purpose of uncomplicated malariais to eliminateplasmodiumcause infection to preventinfectionseverity, complications andbreak the chain oftransmission. While the purpose therapyof severemalaria is to prevent mortality.Recommendedtherapy of malaria isa combination of twoormore antimalarial drugsthat mechanisms actionkillsmalarialparasitesin thebloodand theamount of each drugworks ondifferent receptors. The use ofa combination ofseveralantimalarial drugshas becomea necessityforprevention ofmalariaparasitestrainsthat are resistantto certain drugs. Combination therapyinclude:ACTs(artemisinin combinationtherapies); artesunateandamodiaquin; artesunateandmefloquin; artesunatewith oneof theSP, lumefantrin, piperaquin, pyronaridin; antibiotic(doxyciclin, clindamycine, azithromycin), artemether-lumefantrine (AL); chloroquineandSP;atovaquoneandproguanil (Malarone)

Item Type:	Journal Article
Keywords:	malaria; mekanisme; antimalaria
Subjects:	11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology
Divisions:	Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User:	Dr. M.Kes. Roihatul Muti'ah
Date Deposited:	27 Apr 2017 17:47

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