Muchtaromah, Bayyinatul, Maulahibati, Farah Fauzia, Fitriasari, Prilya Dewi 
ORCID: https://orcid.org/0000-0002-5698-3021, Ahmad, Mujahidin and Minarno, Eko Budi ORCID: https://orcid.org/0000-0003-0793-4802
(2025)
The effect of Allium sativum, Curcuma mangga, and Acorus calamus nanoparticles to profile of mice leukocytes induced by cisplatin.
Presented at THE 5TH INTERNATIONAL CONFERENCE ON LIFE SCIENCE AND TECHNOLOGY (ICoLiST), 30–31 August 2022, Malang, Indonesia.
|
Text
8. AIP PROCEEDING 30012025 Prof Bayyinatul dkk .pdf - Published Version Download (1MB) | Preview |
Abstract
The induction of cisplatin can increase the production of reactive oxygen species (ROS) and cause an imbalance
in the immune system. This condition can be overcome with use of A. sativum, C. mangga, and A. calamus. That plants
contain several active compounds to improve the function of the immune system, including leukocytes. This study aimed
to know the effect of nanoparticles A. sativum, C. mangga, and A. calamus on the total cell leukocyte and total leukocyte
types (neutrophil, basophil, eosinophil, lymphocyte, and monocyte) in mice that induced by cisplatin. This study used the
Complete Random Design (CRD) with 5 treatments and 6 replicates. The examination of the total leukocyte used a
hemocytometer and the total leukocyte types used a blood smear. The results showed that there was an effect of giving
nanoparticles A. sativum, C. mangga, and A. calamus on the total leukocyte, neutrophils, and lymphocytes mice and there
was no effect of giving nanoparticles A. sativum, C. mangga, and A. calamus to basophils and eosinophils mice that are
induced by cisplatin. The dose of nanoparticles extracts A. sativum, C. mangga, and A. calamus 25 mg/kgBW and 50
mg/kgBW had a significant effect compared to the other treatment groups.
| Item Type: | Conference (Paper) |
|---|---|
| Keywords: | Allium sativum, Acorus calamus, Cisplatin, Curcuma mangga, Nanoparticles |
| Subjects: | 06 BIOLOGICAL SCIENCES > 0608 Zoology > 060802 Animal Cell and Molecular Biology 06 BIOLOGICAL SCIENCES > 0608 Zoology 06 BIOLOGICAL SCIENCES > 0699 Other Biological Sciences |
| Divisions: | Faculty of Mathematics and Sciences > Department of Biology |
| Depositing User: | Prilya Dewi Fitriasari |
| Date Deposited: | 08 Dec 2025 14:50 |
Downloads
Downloads per month over past year
Origin of downloads
Actions (login required)
 |
View Item |
Altmetric
Altmetric