Vanadium accumulation in ascidians: A system overview

Ueki, Tatsuya and Yamaguchi, Nobuo and Romaidi, Romaidi and Isago, Yoshiaki and Tanahashi, Hisashi (2015) Vanadium accumulation in ascidians: A system overview. Coordination Chemistry Reviews, 301. pp. 300-308. ISSN 00108545

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Several families of ascidians accumulate extremely high levels of vanadium in their blood cells. The concentration of vanadium has been determined in each species; the highest concentration, found in Ascidia gemmata, reaches 350mM, corresponding to 107 times that of sea water. How and why ascidians accumulate vanadium in a highly selective manner and at such extremely high levels have yet to be determined. To address these questions, our research group sought to identify the genes and proteins responsible for the accumulation and reduction of vanadium in vanadocytes, a type of blood cell, as well as the process of vanadium transport from sea water to blood cells through the branchial sac, intestine, and blood plasma. Here, we review the accumulation steps as a system, especially those related to the concentration and chemical species of vanadium at each step. A comprehensive analysis on each organ has already revealed several categories of protein families, such as vanadium-binding proteins and vanadium transporters. Herein, we also discuss the mechanisms by which ascidians selectively accumulate vanadium ions from a biochemical viewpoint.

Item Type: Journal Article
Keywords: Ascidian; Membrane transporters; Metal-binding proteins; Reductase; Vanadium
Divisions: Faculty of Mathematics and Sciences > Department of Biology
Depositing User: Indar Ristamonika Erdiana
Date Deposited: 25 May 2018 15:23


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