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Jati, Alpian Rona Asmoro, Sugihantoro, Hajar 
ORCID: https://orcid.org/0000-0001-5451-657X and Syahrir, Ach.
(2025)
Cost effectiveness analysis of hypertensive therapy in hypertensive patients with type 2 of diabetes mellitus at RSUD Dr. Soehadi Prijonegoro Sragen.
Jurnal Farmasi Galenika, 11 (1).
pp. 34-48.
ISSN 2442-8744
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Abstract
Hypertension followed by type 2 diabetes mellitus is a major risk factor for various cardiovascular diseases and is one of the chronic degenerative diseases Hence, it requires long-lasting treatment therapy and highcosts. Based on this, hypertensive patients with DM type 2 need special attention in order to get effective hypertensive therapy at minimum cost. Cost-effectiveness analysis is an analytical method for makingdecisions on the best alternative to the therapy used.Objectives: Todetermine the most cost-effective hypertensive therapy in hypertensive patients with DM type 2 diabetes who underwent pharmacoeconomic hospitalization with a cost-effectiveness analysis approach. Methods: This type of study is descriptive observational with a retrospective data collection method fromJanuary 2021 –June 2023. The data taken was 31 medical recordsdata and bill fees that met the inclusion criteria. Results:The description of drug use in hypertensive patients with DM type 2 diabetes at RSUD Soehadi Prijonegoro Sragen consists of monotherapy (19.35%) and combination (80.65%). The effectiveness of monotherapy was highest in patients receiving amlodipinetherapy (12.42 mmHg), while the effectiveness of the combination was highest in patients taking adalat oros + candesartan + bisoprolol + furosemide+ clonidine (22,38 mmHg). From the calculation of the ACER value, it was found that the most cost-effective drug wasamlodipine, which hadan ACER value of Rp. 289,962 in monotherapy and amlodipine+ candesartan with an ACER value of Rp. 262,626. Conclusions: The most widely used hypertension therapy is combination therapy;the drug with the highest effectiveness is adalat oros + candesartan + bisoprolol + furosemide+ clonidine and the drug with the highest cost-effectiveness is amlodipinemonotherapy and the combination of amlodipine+ candesartan
| Item Type: | Journal Article |
|---|---|
| Keywords: | Cost-effectiveness analysis; Hypertension therapy; Type 2 diabetes mellitus |
| Subjects: | 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111711 Health Information Systems (incl. Surveillance) |
| Divisions: | Faculty of Medical and Health Sciences > Department of Pharmacy |
| Depositing User: | Hajar Sugihantoro |
| Date Deposited: | 09 Dec 2025 15:51 |
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