Assessment of the phytochemicals and anthelminthic activities of Adiantum raddianum and Kibatalia arborea extracts

Yogisuari, Ghita, Rachma, Lailia Nur ORCID: https://orcid.org/0000-0003-0199-9656, Reza, Rocky Fahriar, Raras, Tri Yudani Mardining, Triatmoko, Bawon ORCID: https://orcid.org/0000-0002-7963-9602, Pratama, Antonius Nugraha Widhi and Nugraha, Ari Satia ORCID: https://orcid.org/0000-0001-9106-9924 (2023) Assessment of the phytochemicals and anthelminthic activities of Adiantum raddianum and Kibatalia arborea extracts. Pharmacy Education, 23 (4). pp. 284-288. ISSN 1477-2701

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Abstract

Background: A limited spectrum and inappropriate use of anthelmintics lead to anthelmintic resistance. Among Indonesian medicinal plants, Adiantum raddianum (Suplir) and Kibatalia arborea (Jelutong Pipit) have shown antihelmintic properties.

Objective: To reveal the anthelmintic activity as preliminary screening of A. raddianum and K. arborea leaves.

Method: This study used the antihelmintic microdilution test towards methanol extracts at 500 µg/mL. The mortality of Caenorhabditis elegans expresses the presence of anthelmintic activity. Phytochemical screening was determined using thin-layer chromatography.

Result: The methanol extracts of both extracts had anthelmintic activity with mortality values of 14.941% and 15.134%, respectively. Both extracts contain polyphenols, flavonoids, terpenoids, and alkaloids found only in K. arborea.

Conclusion: This study reveals that the methanol extract of A. raddianum and K. arborea leaves have anthelmintic activity, which could be related to the findings of phytochemical constituents.

Item Type:	Journal Article
Keywords:	Caenorhabditis elegans; Jelutong pipit; Microdilution; Suplir; Thin layer chromatography
Subjects:	11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology
Divisions:	Faculty of Medical and Health Sciences > Department of Medical Education
Depositing User:	Lailia Rachma
Date Deposited:	01 Jan 2026 12:15

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