Level of Folic Acid and Vitamin B12 in Mothers and Children with Neural Tube Defect

Utami, Amalia Tri and Baktiyani, Siti Chandra Windu and Santosa, Moch. Istiadjid Eddy (2016) Level of Folic Acid and Vitamin B12 in Mothers and Children with Neural Tube Defect. Asian Journal of Clinical Nutrition, 8 (1). pp. 14-18. ISSN 1992-1470

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Full text available at: http://doi.org/10.3923/ajcn.2016.14.18

Abstract

Abstract: Background and Objective: Neural Tube Defect (NTD) is the leading cause of death in infants younger than one year. Incidence of congenital anomalies has approximately 1 in 1000 live births in the United States. Less dietary folic acid and vitamin B12 in the mother during the critical period of pregnancy reported to play a role in the occurrence of neural tube defects. The aim of this study was compared the level of folic acid and vitamin B12 in both mother and her child with and without NTD. Methodology: This study was cross-sectional design and will be examined levels of folic acid in six mothers and children with and without neural tube defect in Saiful Anwar Hospital during September, 2009 until September, 2013. Results: This study showed no significant differences of folic acid and vitamin B12 level between NTD and control group in mothers (p>0.05). The study also showed no significant differences of folic acid and vitamin B12 level between NTD group and control group in children (p>0.05). Conclusion: The level of folic acid and vitamin B12 in the mother having neural tube defect child as much as the mother with haven’t neural tube defect child. Additionally, the result of the children above a year with neural tube defect and without neural tube defect has same folic acid and vitamin B12 level.

Item Type: Journal Article
Divisions: Faculty of Medical and Health Sciences > Department of Medical Education
Depositing User: Faizuddin Harliansyah
Date Deposited: 06 Jun 2018 22:15

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