Histological description of small intestine and kidney of white rats (Rattus norvegicus) infected with Salmonella typhi by giving earthworm flour

Muchtaromah, Bayyinatul and Maslikah, Siti Imroatul and Mufarrichah, Lailil and Fitriasari, Prilya Dewi (2020) Histological description of small intestine and kidney of white rats (Rattus norvegicus) infected with Salmonella typhi by giving earthworm flour. Presented at International Conference on Biology and Applied Science (ICOBAS), 20 Maret 2019, Malang, East Java, Indonesia.

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Full text available at: https://aip.scitation.org/doi/10.1063/1.5115720

Abstract

Earthworms (Lumbricus rubellus) can be used as medicine for typhus caused by Salmonella typhi. The active compounds in earthworms include lysozyme, agglutinin, lytic factor, and lumbricine. The treatment of flour worms with concentration and duration of administration improperly influence the S. typhi inhibition in vivo. This study aimed to determine the effect of concentration and duration of worm flour administration on the histological description of the small intestine and kidney of white rats (R. norvegicus) infected with the S. typhi. The first factor was the concentration of worm flour (32%, 48% and 60%), and the second factor was the duration of administration (7 days and 14 days). Data were analyzed by two-way ANOVA. The results showed that the concentration and duration of worm flour administration affected improving the histological damage of the small intestine and kidneys of rats, but the interaction of concentration and duration of worm flour administration did not show a significant effect. The effective treatment was found at a concentration of 60%, with a duration of 14 days

Item Type: Conference (Paper)
Subjects: 06 BIOLOGICAL SCIENCES > 0605 Microbiology
06 BIOLOGICAL SCIENCES > 0608 Zoology
Depositing User: Prilya Dewi Fitriasari
Date Deposited: 23 Nov 2020 14:28

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