The profile of anticancer activities of Sambiloto extract (Andrographis paniculata Nees) from several locations in East Java

Mutiah, Roihatul and Luthfiana, Fina and Suryadinata, Arief and Anggraini, Wirda and Listiyana, Anik (2020) The profile of anticancer activities of Sambiloto extract (Andrographis paniculata Nees) from several locations in East Java. Journal of Food and Pharmaceutical Sciences, 8 (1). pp. 194-202. ISSN 2339-0948

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Abstract

Sambiloto (Andrographis paniculata Nees) contains andrographolid compound which has potential as an anticancer. The difference of growth location has affected the distinction of metabolite content. This study aims to determine the profile of anticancer activities of A. paniculata extract from several locations in East Java. The extracts from several locations were tested for activity on T47D cancer cell using MTT assay method. Thus, the result of this study describes that A. paniculata extract from several different locations does not provide significantly different anticancer activities with the amount of (p>0.05). The extracts which have moderate anticancer activity were A. paniculata extracts from Selopuro Subdistrict Blitar Regency, Singosari Subdistrict Malang Regency, Lowokwaru Subdistrict Malang City, Klojen Subdistrict Malang City, Purwodadi Subdistrict Pasuruan Regency, Purwosari Subdistrict Pasuruan Regency, and Pandaan Subdistrict Pasuruan Regency.

Item Type: Journal Article
Keywords: Andrographis paniculata Nees; East Java; MTT assay; activity profile
Subjects: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified
Divisions: Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User: Dr. M.Kes. Roihatul Muti'ah
Date Deposited: 27 Nov 2020 15:49

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