Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines

Mutiah, Roihatul, Sukardiman, Sukardiman, Widyawaruyanti, Aty and Zulaikah, Siti (2016) Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines. Alchemy, 5 (1). pp. 1-4. ISSN 2086-1710

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Abstract

This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea. This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC50 459.51 μg/mL) and the flowers(IC50>1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast
cancer.

Item Type:	Journal Article
Keywords:	Ethanol Extract; Roots; Leaves; Flowers; Calotropis gigantea; Anticancer; T47D Breast Cancer; Cell Lines
Subjects:	03 CHEMICAL SCIENCES > 0304 Medicinal and Biomolecular Chemistry > 030401 Biologically Active Molecules 11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111501 Basic Pharmacology
Divisions:	Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User:	Dr. M.Kes. Roihatul Muti'ah
Date Deposited:	19 Oct 2016 05:51

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