Analysis of powder properties and pharmacopeial spesifications of bagasse cellulose isolated from Saccharum officinarum l in Indonesia

Fauziyah, Begum and Yuwono, M. and Isnaeni, Isnaeni (2021) Analysis of powder properties and pharmacopeial spesifications of bagasse cellulose isolated from Saccharum officinarum l in Indonesia. Indian Journal of Forensic Medicine & Toxicology, 15 (3). pp. 2154-2163. ISSN 09739122, 09739130

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Abstract

Saccharum Officinarum L is native to Asian countries, including Asia. Indonesia is the third-largest sugarcane
producer in the ASEAN region. The amount of sugarcane production represents the potential amount of
bagasse waste obtained. Bagasse has not been used properly and optimally in Indonesia. Bagasse contains
43.6% cellulose; hemicellulose 33.8%; lignin 18.1%; ash 2.3% and wax 0.8%. The purpose of this study
was to isolate bagasse cellulose with 5% of nitric acid. We determined the organoleptic powder properties
and pharmacopeial specifications of bagasse cellulose as pharmaceutical raw materials. As a result, the test
parameters as pharmaceutical raw materials for bagasse cellulose met the requirements compared to Japan
Pharmacopeia XV except for the ash content value. Bagasse cellulose powder had a white color, a water
content of 5.93%, and pH 6.7. It was insoluble in water-ethanol and ether and had Pb-Cr-Cd metal content
<10 ppm. The microbial limits were below the specified requirements. The ash content was 0.6, the bulk
density was 0.136, the tapped density was 0.158, Carr’s index was 13.92, the Hausner ratio was 1.162, and
the angle of repose was 56.4. Based on the angle of repose value, bagasse cellulose powder had fairly good
flow properties

Item Type: Journal Article
Keywords: Powder Properties, Pharmacopeial Spesifications, Bagasse Cellulose, Saccharum Officinarum L
Subjects: 03 CHEMICAL SCIENCES > 0301 Analytical Chemistry > 030101 Analytical Spectrometry
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030502 Natural Products Chemistry
03 CHEMICAL SCIENCES > 0305 Organic Chemistry
Divisions: Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User: Begum Fauziyah
Date Deposited: 23 Jun 2021 21:05

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