Gambir extract nanoemulgel formulation based on maggot oil as oil phase

Annaura, Syifa, Ferdianiko, Irfan Yogik, Amin, Akhfas Faisal, Rahmayanti, Mayu ORCID: https://orcid.org/0000-0002-7356-1488, Lestari, Ria Indah and Salsabila, Dhia Fadhilah (2022) Gambir extract nanoemulgel formulation based on maggot oil as oil phase. Akta Kimia Indonesia, 7 (2). pp. 107-119. ISSN 25493736

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Abstract

Gambir extract is the extraction result of gambir plant (Uncaria gambir) which contains polyphenol compounds. The gambir extract encompasses catechins which act as antimicrobials and antioxidants. The nanoemulgel formulation in this study utilized 9% gambir extract (Uncaria gambir) as the active ingredient and 1% Black Soldier Fly (BSF) maggot oil as the oil phase in the manufacture of nanoemulsions. The emulsification method was administered by implementing a magnetic stirrer with a spontaneous mixing technique. Nanoemulsion characterization employed is the Particle Size Analyzer (PSA) encompassed particle size, polydispersity index, and zeta potential, hence, the results were in accordance with nano criteria, that were 382.27 ± 72.28 nm, 0.29 ± 0.14, and -0.57 ± 1.28 mV respectively. The physical evaluation of nanoemulgel incorporated organoleptic tests, homogeneity, pH with a value of 6.23 ± 0.31, spreadability with a value of 5.83 ± 0.15 g.cm/second, and adhesion with a value of 7.33 ± 0.90 seconds which fulfilled the criteria for nanoemulgel preparation.

Item Type:	Journal Article
Keywords:	Gambir extract; maggot oil; nanoemulgel
Subjects:	11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111504 Pharmaceutical Sciences
Divisions:	Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User:	Mayu Rahmayanti
Date Deposited:	22 May 2023 12:39

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