Effect of earthworm (Lumbricus rubellus) flour against histological profile of several organs and transaminase enzyme level in rat that infected by Salmonella typhi

Muchtaromah, Bayyinatul and Andriani, Amalia Fitri Effect of earthworm (Lumbricus rubellus) flour against histological profile of several organs and transaminase enzyme level in rat that infected by Salmonella typhi. Presented at Workshop on Plant Products Chemistry and International Symposium on Medicinal-Aromatic Plants, June 4-7, 2013, Kaya Izmir Thermal & Convention Balcova, Izmir, Turkey. (Unpublished)

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Abstract

Based on empirical experience, earthworms can be used as a cure varios diseases in humans,one of them is typhus that caused by Salmonella typhi bacterium. In East Java Indonesia, the use of earthworms as a traditional medicine has long been used as a cure typhoid fever. To facilitate the treatment, medicine was made in the form of powder or flour that made from Lumbricus rubellus as base material. The aims of this study to determine the optimal dose and duration of administration in the treatment of diseases caused by infection Salmonella typhi bacteria in vivo. This study was an experimental study using Completely Randomized Design with two factors. The first factor was the dose of flour worms (dose 32%, 48%, and 60%). The second factor was the duration of administration (7 days and 14 days). The results showed that the dose and duration of administration flour worms effected the repairing of histological profile of the small intestine, kidney and hepar and decreasing of transaminase enzyme level, but the interaction of dose and duration of administration did not show any significant effect. Effective dose that effected repairing several organs profile and decreasing Level of Transaminase enzyme was the concentration of 60%, and duration of administration which effectively was Duration of 14 days.

Item Type: Conference (Speech)
Keywords: Earthworm flour; Lubricus rubellus; small intestine; kidney; hepar histology; rat; transaminase; enzyme level; salmonella typhi
Subjects: 06 BIOLOGICAL SCIENCES > 0601 Biochemistry and Cell Biology > 060107 Enzymes
Divisions: Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User: Bayyinatul Muchtaromah
Date Deposited: 18 Apr 2017 03:31

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