The activity of purple sweet potato leaves (Ipomea batatas Ver.) extract to calcium oxalate concentration of male rat (Rattus novergicus)

Mutiah, Roihatul and Fitrianingsih, Avin Ainur and Indrawijaya, Yen Yen Ari and Rahmadani, Nabila (2020) The activity of purple sweet potato leaves (Ipomea batatas Ver.) extract to calcium oxalate concentration of male rat (Rattus novergicus). Majalah Obat Tradisional, 25 (1). pp. 49-53. ISSN 1410-5918

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Abstract

Purple sweet potato leaves (Ipomea batatasVer.) has been proven to have anti-lithiasis effects in vitro in treating kidneystone disease. This is due to the high content of potassium in the leaves. The study aimed to analyze the effect of purple sweet potato leaf extract on kidney stone decay inmale white rats induced by ethylene glycol 0.75% and ammonium chloride 2% for 10 days. In this study, 24 mice were divided into 6 groups: normal or without induction group, positive control, negative control, dose group 300 mg/200-gram body weight, 400 mg/200-gram body weight, and 500 mg/200-gram body weight. The parameters observed were calcium levels in the urine tested using Atomic Absorption Spectrophotometry, oxalate levels in urine tested using UV VIS Spectrophotometer. The results of this study indicate that purple sweet potato leaf extract at a dose of 500 mg/200-gram body weight can increase the levels of calcium and oxalate in the urine of rats compared with negative controls

Item Type: Journal Article
Keywords: Ipomea batatasVer.; calcium; oxalate; ethylene glycol; ammonium chloride
Subjects: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110312 Nephrology and Urology
11 MEDICAL AND HEALTH SCIENCES > 1104 Complementary and Alternative Medicine > 110499 Complementary and Alternative Medicine not elsewhere classified
Divisions: Faculty of Medical and Health Sciences > Department of Pharmacy
Depositing User: Yen Yen Indrawijaya
Date Deposited: 08 Sep 2020 09:04

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